Inside WHMCS is a very good ticket system. I suggest you use it for both billing and support!
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If you're doing Shared/VPS hosting then WHMCS is good as it integrates well with control panels and VPS OSs.
If you're more into dedicated servers then Ubersmith is the better bet.
The key is to pick a system that provides the features you're looking for at a price you can afford. Augment that with phone and knowledge base support to meet customer expectations and you'll have a system that's best for you.
WHMCS has proven to be one of the best complete system for hosting business. It not only includes a complete support system but also billing too. Hence, you do not need any thing else if you have WHMCS.
It only lacks Live Chat option, because you have to pay more for it. So, you may Live Zilla for it.
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It is very usefull to keep billing, support and livechat history on the same system.
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